1BOWTIE2-BUILD(1) User Commands BOWTIE2-BUILD(1)
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6 bowtie2-build - manual page for bowtie2-build 2.5.1
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9 bowtie2-build [options]* <reference_in> <bt2_index_base>
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12 Bowtie 2 version 2.5.1 by Ben Langmead (langmea@cs.jhu.edu,
13 www.cs.jhu.edu/~langmea)
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15 reference_in
16 comma-separated list of files with ref sequences
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18 bt2_index_base
19 write bt2 data to files with this dir/basename
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21 *** Bowtie 2 indexes will work with Bowtie v1.2.3 and later. *** Op‐
22 tions:
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24 -f reference files are Fasta (default)
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26 -c reference sequences given on cmd line (as <reference_in>)
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28 --large-index
29 force generated index to be 'large', even if ref has fewer than
30 4 billion nucleotides
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32 --debug
33 use the debug binary; slower, assertions enabled
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35 --sanitized
36 use sanitized binary; slower, uses ASan and/or UBSan
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38 --verbose
39 log the issued command
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41 -a/--noauto
42 disable automatic -p/--bmax/--dcv memory-fitting
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44 -p/--packed
45 use packed strings internally; slower, less memory
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47 --bmax <int>
48 max bucket sz for blockwise suffix-array builder
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50 --bmaxdivn <int>
51 max bucket sz as divisor of ref len (default: 4)
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53 --dcv <int>
54 diff-cover period for blockwise (default: 1024)
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56 --nodc disable diff-cover (algorithm becomes quadratic)
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58 -r/--noref
59 don't build .3/.4 index files
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61 -3/--justref
62 just build .3/.4 index files
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64 -o/--offrate <int>
65 SA is sampled every 2^<int> BWT chars (default: 5)
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67 -t/--ftabchars <int>
68 # of chars consumed in initial lookup (default: 10)
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70 --threads <int>
71 # of threads
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73 --seed <int>
74 seed for random number generator
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76 -q/--quiet
77 verbose output (for debugging)
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79 --h/--help
80 print this message and quit
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82 --version
83 print version information and quit
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87bowtie2-build 2.5.1 July 2023 BOWTIE2-BUILD(1)